Metabolic Engineering of Terpenoid Biosynthesis in Plants

Compartmentation of Terpenoid Biosynthesis in Green Plants

On the basis of radioisotope-incorporation experiments it is suggested that acetyl-CoA, an obligatory intermediate in chloroplast terpenoid biosynthesis, may be formed inmaize from photosynthetically fixed carbon dioxide by the route carbon dioxide --> glycollate -÷ glyoxylate -* glycine --serine --> pyruvate -acetyl-CoA. The proposed route is supported by conventional radioisotope-dilution stu...

Alkaloid Biosynthesis -The Basis for Metabolic Engineering of Medicinal Plants

Metabolic Engineering of Synechocystis sp. PCC 6803 for Terpenoid Production

Englund, E. 2016. Metabolic Engineering of Synechocystis sp. PCC 6803 for Terpenoid Production. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1455. 63 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9761-3. In the Paris Agreement from 2015, nations agreed to limit the effects of global warming to well below 2°C. To be able to re...

Essences in Metabolic Engineering of Lignan Biosynthesis

Lignans are structurally and functionally diverse phytochemicals biosynthesized in diverse plant species and have received wide attentions as leading compounds of novel drugs for tumor treatment and healthy diets to reduce of the risks of lifestyle-related non-communicable diseases. However, the lineage-specific distribution and the low-amount of production in natural plants, some of which are ...

Triterpenoid Biosynthesis and Engineering in Plants

Triterpenoid saponins are a diverse group of natural products in plants and are considered defensive compounds against pathogenic microbes and herbivores. Because of their various beneficial properties for humans, saponins are used in wide-ranging applications in addition to medicinally. Saponin biosynthesis involves three key enzymes: oxidosqualene cyclases, which construct the basic triterpen...